产品货号：
Z28179
中文名称：
TGFBR1抗体
英文名称：
Anti-TGFBR1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TGFBR1 Antibody |
| 指标别名 | transforming growth factor beta receptor 1;AAT5;ACVRLK4;ALK-5;ALK5;ESS1;LDS1;LDS1A;LDS2A;MSSE;SKR4;TBR-i;TBRI;TGFR-1;tbetaR-I;TGFBR1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | TGFBR1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human TGFBR1 (149-186aa HNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTT),identical to the related mouse and rat sequences. |
| 实际分子量 | 56KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Transforming growth factor,beta receptor I is a TGF beta receptor.TGFBR1 is its human gene.The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta,transducing the TGF-beta signal from the cell surface to the cytoplasm.Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).TGFB1 regulates cell cycle progression by a unique signaling mechanism that involves its binding to TGFBR2 and activation of TGFBR1.Both are transmembrane serine/threonine receptor kinases.The TGFBR1 receptor may be inactivated in many of the cases of human tumor cells refractory to TGFB-mediated cell cycle arrest.Vellucci and Reiss (1997) reported that the TGFBR1 gene is approximately 31kb long and contains 9 exons.The organization of the segment of the gene that encodes the C-terminal portion of the serine/threonine kinase domain appears to be highly conserved among members of the gene family. |
| Uniprot ID | P36897 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | transforming growth factor,beta receptor 1 |
| 蛋白名全称 | TGF-beta receptor type-1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：TGFBR1抗体，TGFBR1多抗，Anti-TGFBR1 Antibody